I am having the same problem described in this thread. Not consistently, but on some flights during cruise the FD commands nearly full pitch up, and I lose thrust even though I move the levers to full power. The aircraft loses speed until around 130-140 kts, and loses altitude. I fiddled a bunch with the elevator control and performed a full stall and recovery, and that seemed to reset whatever was broken and I was able to continue on my way normally.
also, this is a distinct issue from the invisible spoiler deployment after hitting the ESC key.